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Y-27632 Impairs Angiogenesis on Extra-Embryonic Vasculature in Post-Gastrulation Chick Embryos

Y-27632 inhibits Rho-associated coiled-coil-containing protein kinase (ROCK) signaling, which is involved in various embryonic developmental processes, including angiogenesis, by controlling actin cytoskeleton assembly and cell contractility. Administration of Y-27632 impairs cytoskeletal arrangemen...

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Detalles Bibliográficos
Autores principales: Duess, Johannes W., Gosemann, Jan-Hendrik, Kaskova Gheorghescu, Anna, Puri, Prem, Thompson, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962381/
https://www.ncbi.nlm.nih.gov/pubmed/36851009
http://dx.doi.org/10.3390/toxics11020134