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Neutralising Effects of Different Antibodies on Clostridioides difficile Toxins TcdA and TcdB in a Translational Approach

Given the high prevalence of intestinal disease in humans and animals, there is a strong need for clinically relevant models recapitulating gastrointestinal systems, ideally replacing in vivo models in accordance with the principles of the 3R. We established a canine organoid system and analysed the...

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Detalles Bibliográficos
Autores principales: Csukovich, Georg, Kramer, Nina, Pratscher, Barbara, Gotic, Ivana, Freund, Patricia, Hahn, Rainer, Himmler, Gottfried, Brandt, Sabine, Burgener, Iwan Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962434/
https://www.ncbi.nlm.nih.gov/pubmed/36835278
http://dx.doi.org/10.3390/ijms24043867