Synthesis and Cytotoxic Activity of the Derivatives of N-(Purin-6-yl)aminopolymethylene Carboxylic Acids and Related Compounds

Testing a number of N-[omega-(purin-6-yl)aminoalkanoyl] derivatives of 7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine in a panel of nine tumor cell lines has shown that the studied compounds exhibit high cytotoxic activity, especially against 4T1 murine mammary carcinoma, COLO201 human colore...

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Detalles Bibliográficos
Autores principales: Krasnov, Victor P., Vozdvizhenskaya, Olga A., Baryshnikova, Maria A., Pershina, Alexandra G., Musiyak, Vera V., Matveeva, Tatyana V., Nevskaya, Kseniya V., Brikunova, Olga Y., Gruzdev, Dmitry A., Levit, Galina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962735/
https://www.ncbi.nlm.nih.gov/pubmed/36838839
http://dx.doi.org/10.3390/molecules28041853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962735/
https://www.ncbi.nlm.nih.gov/pubmed/36838839
http://dx.doi.org/10.3390/molecules28041853

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