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Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development

At high levels, extracellular ATP operates as a “danger” molecule under pathologic conditions through purinergic receptors, including the ionotropic P2X7 receptor (P2X7R). Its endogenous activation is associated with neurodevelopmental disorders; however, its function during early embryonic stages r...

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Detalles Bibliográficos
Autores principales: Mut-Arbona, Paula, Huang, Lumei, Baranyi, Mária, Tod, Pál, Iring, András, Calzaferri, Francesco, de los Ríos, Cristobal, Sperlágh, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962779/
https://www.ncbi.nlm.nih.gov/pubmed/36732073
http://dx.doi.org/10.1523/JNEUROSCI.0805-22.2022