The D405N Mutation in the Spike Protein of SARS-CoV-2 Omicron BA.5 Inhibits Spike/Integrins Interaction and Viral Infection of Human Lung Microvascular Endothelial Cells

Severe COVID-19 is characterized by angiogenic features, such as intussusceptive angiogenesis, endothelialitis, and activation of procoagulant pathways. This pathological state can be ascribed to a direct SARS-CoV-2 infection of human lung ECs. Recently, we showed the capability of SARS-CoV-2 to inf...

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Detalles Bibliográficos
Autores principales: Bugatti, Antonella, Filippini, Federica, Messali, Serena, Giovanetti, Marta, Ravelli, Cosetta, Zani, Alberto, Ciccozzi, Massimo, Caruso, Arnaldo, Caccuri, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962894/
https://www.ncbi.nlm.nih.gov/pubmed/36851546
http://dx.doi.org/10.3390/v15020332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962894/
https://www.ncbi.nlm.nih.gov/pubmed/36851546
http://dx.doi.org/10.3390/v15020332

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