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(68)Ga-Labeled [Thz(14)]Bombesin(7–14) Analogs: Promising GRPR-Targeting Agonist PET Tracers with Low Pancreas Uptake

With overexpression in various cancers, the gastrin-releasing peptide receptor (GRPR) is a promising target for cancer imaging and therapy. However, the high pancreas uptake of reported GRPR-targeting radioligands limits their clinical application. Our goal was to develop (68)Ga-labeled agonist trac...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Bratanovic, Ivica Jerolim, Zhang, Zhengxing, Kuo, Hsiou-Ting, Merkens, Helen, Zeisler, Jutta, Zhang, Chengcheng, Tan, Ruiyan, Bénard, François, Lin, Kuo-Shyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962964/
https://www.ncbi.nlm.nih.gov/pubmed/36838968
http://dx.doi.org/10.3390/molecules28041977