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Polyacetylene Isomers Isolated from Bidens pilosa L. Suppress the Metastasis of Gastric Cancer Cells by Inhibiting Wnt/β-Catenin and Hippo/YAP Signaling Pathways

(E)-7-Phenyl-2-hepten-4,6-diyn-1-ol (1) and (Z)-7-Phenyl-2-hepten-4,6-diyn-1-ol (2) are isomeric natural polyacetylenes isolated from the Chinese medicinal plant Bidens pilosa L. This study first revealed the excellent anti-metastasis potential of these two polyacetylenes on human gastric cancer HGC...

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Detalles Bibliográficos
Autores principales: Cai, Jing, Shi, Song-Yun, Cheng, Fan, Wei, Min, Zou, Kun, Yu, Xiao-Qin, Chen, Jian-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962988/
https://www.ncbi.nlm.nih.gov/pubmed/36838824
http://dx.doi.org/10.3390/molecules28041837