Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis

Cardiac fibrosis is a primary contributor to heart failure (HF), and is considered to be a targetable process for HF therapy. Cardiac fibroblast (CF) activation accompanied by excessive extracellular matrix (ECM) production is central to the initiation and maintenance of fibrotic scarring in cardiac...

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Detalles Bibliográficos
Autores principales: Subbaiah, Kadiam C. Venkata, Wu, Jiangbin, Tang, Wai Hong Wilson, Yao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963048/
https://www.ncbi.nlm.nih.gov/pubmed/36826549
http://dx.doi.org/10.3390/jcdd10020052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963048/
https://www.ncbi.nlm.nih.gov/pubmed/36826549
http://dx.doi.org/10.3390/jcdd10020052

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