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Suppression of Macrophage Activation by Sodium Danshensu via HIF-1α/STAT3/NLRP3 Pathway Ameliorated Collagen-Induced Arthritis in Mice

It is still a clinical challenge to sustain the remission of rheumatoid arthritis (RA); thus, identifying more effective and safer agents for RA treatment remains an urgent demand. We investigated the anti-arthritic activity and potential mechanism of action of sodium Danshensu (SDSS), a structurall...

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Detalles Bibliográficos
Autores principales: Wu, Danbin, Xu, Jia, Jiao, Wei, Liu, Lijuan, Yu, Jiahui, Zhang, Mingying, Chen, Guangxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963181/
https://www.ncbi.nlm.nih.gov/pubmed/36838542
http://dx.doi.org/10.3390/molecules28041551