Endothelial Differentiation of CCM1 Knockout iPSCs Triggers the Establishment of a Specific Gene Expression Signature

Cerebral cavernous malformation (CCM) is a neurovascular disease that can lead to seizures and stroke-like symptoms. The familial form is caused by a heterozygous germline mutation in either the CCM1, CCM2, or CCM3 gene. While the importance of a second-hit mechanism in CCM development is well estab...

Descripción completa

Detalles Bibliográficos
Autores principales: Pilz, Robin A., Skowronek, Dariush, Mellinger, Lara, Bekeschus, Sander, Felbor, Ute, Rath, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963194/
https://www.ncbi.nlm.nih.gov/pubmed/36835400
http://dx.doi.org/10.3390/ijms24043993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963194/
https://www.ncbi.nlm.nih.gov/pubmed/36835400
http://dx.doi.org/10.3390/ijms24043993

Ejemplares similares