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Cancer Vaccines Based on Fluorine-Modified KH-1 Elicit Robust Immune Response

KH-1 is a tumor-associated carbohydrate antigen (TACA), which serves as a valuable target of antitumor vaccines for cancer immunotherapies. However, most TACAs are thymus-independent antigens (TD-Ag), and they tend to induce immunological tolerance, leading to their low immunogenicity. To overcome t...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Li, Bohan, Zheng, Xiujing, Xiong, Decai, Ye, Xinshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963332/
https://www.ncbi.nlm.nih.gov/pubmed/36838925
http://dx.doi.org/10.3390/molecules28041934