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Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion

Oxytocin (OT) is a prominent regulator of many aspects of mammalian social behavior and stored in large dense-cored vesicles (LDCVs) in hypothalamic neurons. It is released in response to activity-dependent Ca(2+) influx, but is also dependent on Ca(2+) release from intracellular stores, which prime...

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Detalles Bibliográficos
Autores principales: Martucci, Lora L., Launay, Jean-Marie, Kawakami, Natsuko, Sicard, Cécile, Desvignes, Nathalie, Dakouane-Giudicelli, Mbarka, Spix, Barbara, Têtu, Maude, Gilmaire, Franck-Olivier, Paulcan, Sloane, Callebert, Jacques, Vaillend, Cyrille, Bracher, Franz, Grimm, Christian, Fossier, Philippe, de la Porte, Sabine, Sakamoto, Hirotaka, Morris, John, Galione, Antony, Granon, Sylvie, Cancela, José-Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963339/
https://www.ncbi.nlm.nih.gov/pubmed/36745816
http://dx.doi.org/10.1073/pnas.2213682120