Pinostrobin and Tectochrysin Conquer Multidrug-Resistant Cancer Cells via Inhibiting P-Glycoprotein ATPase

Enhanced drug efflux through ATP-binding cassette transporters, particularly P-glycoprotein (P-gp), is a key mechanism underlying multidrug resistance (MDR). In the present study, we investigated the inhibitory effects of pinostrobin and tectochrysin on P-gp in MDR cancer cells and the underlying me...

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Detalles Bibliográficos
Autores principales: Wu, I-Ting, Kuo, Chan-Yen, Su, Ching-Hui, Lan, Yu-Hsuan, Hung, Chin-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963356/
https://www.ncbi.nlm.nih.gov/pubmed/37259354
http://dx.doi.org/10.3390/ph16020205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963356/
https://www.ncbi.nlm.nih.gov/pubmed/37259354
http://dx.doi.org/10.3390/ph16020205

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