Cargando…

Pinostrobin and Tectochrysin Conquer Multidrug-Resistant Cancer Cells via Inhibiting P-Glycoprotein ATPase

Enhanced drug efflux through ATP-binding cassette transporters, particularly P-glycoprotein (P-gp), is a key mechanism underlying multidrug resistance (MDR). In the present study, we investigated the inhibitory effects of pinostrobin and tectochrysin on P-gp in MDR cancer cells and the underlying me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, I-Ting, Kuo, Chan-Yen, Su, Ching-Hui, Lan, Yu-Hsuan, Hung, Chin-Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963356/ https://www.ncbi.nlm.nih.gov/pubmed/37259354 http://dx.doi.org/10.3390/ph16020205

Ejemplares similares

In vitro study of pinostrobin propionate and pinostrobin butyrate: Cytotoxic activity against breast cancer cell T47D and its selectivity index
por: Widiandani, Tri, et al.
Publicado: (2023)

Theoretical and Experimental Studies on Inclusion Complexes of Pinostrobin and β-Cyclodextrins
por: Kicuntod, Jintawee, et al.
Publicado: (2018)

Study of the dermal anti-inflammatory, antioxidant, and analgesic activity of pinostrobin
por: González, Alejandro Serna, et al.
Publicado: (2022)

Taxifolin Resensitizes Multidrug Resistance Cancer Cells via Uncompetitive Inhibition of P-Glycoprotein Function
por: Chen, Hsiu-Ju, et al.
Publicado: (2018)

Anticancer effect of tectochrysin in colon cancer cell via suppression of NF-kappaB activity and enhancement of death receptor expression
por: Park, Mi Hee, et al.
Publicado: (2015)

Hepatoprotective effect of pinostrobin against thioacetamide-induced liver cirrhosis in rats
por: Shareef, Suhayla H., et al.
Publicado: (2023)

Pain after thoracotomy: Conquered or to be conquered?
por: Singariya, Geeta, et al.
Publicado: (2023)

Simultaneous Determination of Chrysin and Tectochrysin from Alpinia oxyphylla Fruits by UPLC-MS/MS and Its Application to a Comparative Pharmacokinetic Study in Normal and Dementia Rats
por: Zhao, Xu, et al.
Publicado: (2018)

Induction of apoptosis by pinostrobin in human cervical cancer cells: Possible mechanism of action
por: Jaudan, Alka, et al.
Publicado: (2018)

Pinostrobin Suppresses the α-Melanocyte-Stimulating Hormone-Induced Melanogenic Signaling Pathway
por: Athapaththu, Athapaththu Mudiyanselage Gihan Kavinda, et al.
Publicado: (2023)

Pinostrobin: An Adipogenic Suppressor from Fingerroot (Boesenbergia rotunda) and Its Possible Mechanisms
por: San, Htoo Tint, et al.
Publicado: (2022)

Acacetin and Pinostrobin Inhibit Malignant Breast Epithelial Cell Adhesion and Focal Adhesion Formation to Attenuate Cell Migration
por: Jones, Aaron A., et al.
Publicado: (2020)

Divide and conquer: processive transport enables multidrug transporters to tackle challenging drugs
por: Fluman, Nir, et al.
Publicado: (2014)

Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling
por: Harazono, Yosuke, et al.
Publicado: (2015)

Caffeic Acid Attenuates Multi-Drug Resistance in Cancer Cells by Inhibiting Efflux Function of Human P-Glycoprotein
por: Teng, Yu-Ning, et al.
Publicado: (2020)

Conquer Fear
Publicado: (1949)

Conquering Neutrophils
por: Döhrmann, Simon, et al.
Publicado: (2016)

Pinostrobin inhibits proliferation and induces apoptosis in cancer stem-like cells through a reactive oxygen species-dependent mechanism
por: Jadaun, Alka, et al.
Publicado: (2019)

Development and extraction optimization of baicalein and pinostrobin from Scutellaria violacea through response surface methodology
por: Subramaniam, Shankar, et al.
Publicado: (2015)

A comparative analysis on the binding characteristics of various mammalian albumins towards a multitherapeutic agent, pinostrobin
por: FEROZ, Shevin R., et al.
Publicado: (2014)

Discovery of Pinostrobin as a Melanogenic Agent in cAMP/PKA and p38 MAPK Signaling Pathway
por: Yoon, Jeong-Hyun, et al.
Publicado: (2022)

Conquering the Physics GRE
por: Kahn, Yoni, et al.
Publicado: (2018)

Myc conquers all
por: Wells, William A.
Publicado: (2004)

Compassion Conquers All
por: Rinpoche, Tsem
Publicado: (2014)

She stoops to conquer/
por: Goldsmith, Oliver, 1730?-1774

The grid conquers all
Publicado: (2008)

Cheaters divide and conquer
por: Bomblies, Kirsten
Publicado: (2014)

Is the camel conquering the world?
por: Faye, Bernard
Publicado: (2022)

Nramp: Deprive and conquer?
por: Cellier, M. F. M.
Publicado: (2022)

Probing the Interaction of a Therapeutic Flavonoid, Pinostrobin with Human Serum Albumin: Multiple Spectroscopic and Molecular Modeling Investigations
por: Feroz, Shevin R., et al.
Publicado: (2013)

Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein
por: Min, Hongping, et al.
Publicado: (2017)

Angelika Amon: Conquering the divide
por: Short, Ben
Publicado: (2011)

Les conquerants du cybermonde
por: Nora, Dominique
Publicado: (1995)

Neural networks subtract and conquer
por: Hennequin, Guillaume
Publicado: (2017)

Distributed Cube and Conquer with Paracooba
por: Heisinger, Maximilian, et al.
Publicado: (2020)

Promoting Effect of Pinostrobin on the Proliferation, Differentiation, and Mineralization of Murine Pre-osteoblastic MC3T3-E1 Cells
por: Gu, Chengbo, et al.
Publicado: (2017)

Pinostrobin alleviates chronic restraint stress‑induced cognitive impairment by modulating oxidative stress and the function of astrocytes in the hippocampus of rats
por: Thongrong, Sitthisak, et al.
Publicado: (2023)

Active participation of membrane lipids in inhibition of multidrug transporter P-glycoprotein
por: Kapoor, Karan, et al.
Publicado: (2021)

Conquering the content : a step-by-step guide to online course design /
por: Smith, Robin M., 1962-
Publicado: (2008)

Pinostrobin from Boesenbergia rotunda attenuates oxidative stress and promotes functional recovery in rat model of sciatic nerve crush injury
por: Kongsui, R., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tik1hkfhpb00gt9l3i0t5357cb