Discovery of New Quinolone-Based Diarylamides as Potent B-RAF(V600E)/C-RAF Kinase Inhibitors Endowed with Promising In Vitro Anticancer Activity

The emergence of cancer resistance to targeted therapy represents a significant challenge in cancer treatment. Therefore, identifying new anticancer candidates, particularly those addressing oncogenic mutants, is an urgent medical demand. A campaign of structural modifications has been conducted to...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Ji, Park, Jung Woo, Seo, Sangjae, Cho, Kwang-Hwi, Alanazi, Mohammed M., Bang, Eun-Kyoung, Keum, Gyochang, El-Damasy, Ashraf K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963398/
https://www.ncbi.nlm.nih.gov/pubmed/36834628
http://dx.doi.org/10.3390/ijms24043216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963398/
https://www.ncbi.nlm.nih.gov/pubmed/36834628
http://dx.doi.org/10.3390/ijms24043216

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