Impact of ABCG2 and ABCB1 Polymorphisms on Imatinib Plasmatic Exposure: An Original Work and Meta-Analysis

Adequate imatinib plasma levels are necessary to guarantee an efficacious and safe treatment in gastrointestinal stromal tumor (GIST) and chronic myeloid leukemia (CML) patients. Imatinib is a substrate of the drug transporters ATP-binding cassette subfamily B member 1 (ABCB1) and ATP-binding casset...

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Detalles Bibliográficos
Autores principales: Dalle Fratte, Chiara, Polesel, Jerry, Gagno, Sara, Posocco, Bianca, De Mattia, Elena, Roncato, Rossana, Orleni, Marco, Puglisi, Fabio, Guardascione, Michela, Buonadonna, Angela, Toffoli, Giuseppe, Cecchin, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963452/
https://www.ncbi.nlm.nih.gov/pubmed/36834713
http://dx.doi.org/10.3390/ijms24043303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963452/
https://www.ncbi.nlm.nih.gov/pubmed/36834713
http://dx.doi.org/10.3390/ijms24043303

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