Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids

Kidney organoids generated from induced pluripotent stem cells (iPSC) have proven valuable for studies of kidney development, disease, and therapeutic screening. However, specific applications have been hampered by limited expansion capacity, immaturity, off-target cells, and inability to access the...

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Detalles Bibliográficos
Autores principales: Yousef Yengej, Fjodor A., Jansen, Jitske, Ammerlaan, Carola M. E., Dilmen, Emre, Pou Casellas, Carla, Masereeuw, Rosalinde, Hoenderop, Joost G., Smeets, Bart, Rookmaaker, Maarten B., Verhaar, Marianne C., Clevers, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963523/
https://www.ncbi.nlm.nih.gov/pubmed/36724260
http://dx.doi.org/10.1073/pnas.2216836120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963523/
https://www.ncbi.nlm.nih.gov/pubmed/36724260
http://dx.doi.org/10.1073/pnas.2216836120

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