Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity

Triglyceride (TG) metabolism is highly regulated by angiopoietin-like protein (ANGPTL) family members [Y. Q. Chen et al., J. Lipid Res. 61, 1203–1220 (2020)]. During feeding, ANGPTL8 forms complexes with the fibrinogen-like domain-containing protein ANGPTL4 in adipose tissue to decrease ANGPTL3/8- a...

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Detalles Bibliográficos
Autores principales: Zhen, Eugene Y., Chen, Yan Q., Russell, Anna M., Ehsani, Mariam, Siegel, Robert W., Qian, Yuewei, Konrad, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963551/
https://www.ncbi.nlm.nih.gov/pubmed/36763533
http://dx.doi.org/10.1073/pnas.2214081120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963551/
https://www.ncbi.nlm.nih.gov/pubmed/36763533
http://dx.doi.org/10.1073/pnas.2214081120

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