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Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity
Triglyceride (TG) metabolism is highly regulated by angiopoietin-like protein (ANGPTL) family members [Y. Q. Chen et al., J. Lipid Res. 61, 1203–1220 (2020)]. During feeding, ANGPTL8 forms complexes with the fibrinogen-like domain-containing protein ANGPTL4 in adipose tissue to decrease ANGPTL3/8- a...
Autores principales: | Zhen, Eugene Y., Chen, Yan Q., Russell, Anna M., Ehsani, Mariam, Siegel, Robert W., Qian, Yuewei, Konrad, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963551/ https://www.ncbi.nlm.nih.gov/pubmed/36763533 http://dx.doi.org/10.1073/pnas.2214081120 |
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