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GSH-Activatable Aggregation-Induced Emission Cationic Lipid for Efficient Gene Delivery

The key to gene therapy is the design of biocompatible and efficient delivery systems. In this work, a glutathione (GSH)-activated aggregation-induced-emission (AIE) cationic amphiphilic lipid, termed QM-SS-KK, was prepared for nonviral gene delivery. QM-SS-KK was composed of a hydrophilic biocompat...

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Detalles Bibliográficos
Autores principales: Yuan, Yue-Rui, Liu, Qiang, Wang, Deyu, Deng, Yu-Dan, Du, Ting-Ting, Yi, Wen-Jing, Yang, Sheng-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963561/
https://www.ncbi.nlm.nih.gov/pubmed/36838634
http://dx.doi.org/10.3390/molecules28041645