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Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase
NusG is a transcription elongation factor that stimulates transcription pausing in Gram+ bacteria including B. subtilis by sequence-specific interaction with a conserved pause-inducing (−)(11)TTNTTT(−6) motif found in the non-template DNA (ntDNA) strand within the transcription bubble. To reveal the...
Autores principales: | Vishwakarma, Rishi K., Qayyum, M. Zuhaib, Babitzke, Paul, Murakami, Katsuhiko S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963633/ https://www.ncbi.nlm.nih.gov/pubmed/36745813 http://dx.doi.org/10.1073/pnas.2218516120 |
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