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High-throughput droplet-based analysis of influenza A virus genetic reassortment by single-virus RNA sequencing

The segmented RNA genome of influenza A viruses (IAVs) enables viral evolution through genetic reassortment after multiple IAVs coinfect the same cell, leading to viruses harboring combinations of eight genomic segments from distinct parental viruses. Existing data indicate that reassortant genotype...

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Detalles Bibliográficos
Autores principales: Chen, Kuang-Yu, Karuppusamy, Jayaprakash, O’Neill, Mary B., Opuu, Vaitea, Bahin, Mathieu, Foulon, Sophie, Ibanez, Pablo, Quintana-Murci, Lluis, Ozawa, Tatsuhiko, van der Werf, Sylvie, Nghe, Philippe, Naffakh, Nadia, Griffiths, Andrew, Isel, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963642/
https://www.ncbi.nlm.nih.gov/pubmed/36730204
http://dx.doi.org/10.1073/pnas.2211098120