Novel 2-Thiouracil-5-Sulfonamide Derivatives: Design, Synthesis, Molecular Docking, and Biological Evaluation as Antioxidants with 15-LOX Inhibition

New antioxidant agents are urgently required to combat oxidative stress, which is linked to the emergence of serious diseases. In an effort to discover potent antioxidant agents, a novel series of 2-thiouracil-5-sulfonamides (4–9) were designed and synthesized. In line with this approach, our target...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmed, Naglaa M., Lotfallah, Ahmed H., Gaballah, Mohamed S., Awad, Samir M., Soltan, Moustafa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963659/
https://www.ncbi.nlm.nih.gov/pubmed/36838913
http://dx.doi.org/10.3390/molecules28041925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963659/
https://www.ncbi.nlm.nih.gov/pubmed/36838913
http://dx.doi.org/10.3390/molecules28041925

Ejemplares similares