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PEGylation Prolongs the Half-Life of Equine Anti-SARS-CoV-2 Specific F(ab’)(2)

Therapeutic antibodies-F(ab’)(2) obtained from hyperimmune equine plasma could treat emerging infectious diseases rapidly because of their high neutralization activity and high output. However, the small-sized F(ab’)(2) is rapidly eliminated by blood circulation. This study explored PEGylation strat...

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Detalles Bibliográficos
Autores principales: Xu, Mengyuan, Bi, Jinhao, Liang, Bo, Wang, Xinyue, Mo, Ruo, Feng, Na, Yan, Feihu, Wang, Tiecheng, Yang, Songtao, Zhao, Yongkun, Xia, Xianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963672/
https://www.ncbi.nlm.nih.gov/pubmed/36834803
http://dx.doi.org/10.3390/ijms24043387