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Persistent binding at dopamine transporters determines sustained psychostimulant effects

Psychostimulants interacting with the dopamine transporter (DAT) can be used illicitly or for the treatment of specific neuropsychiatric disorders. However, they can also produce severe and persistent adverse events. Often, their pharmacological properties in vitro do not fully correlate to their ph...

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Detalles Bibliográficos
Autores principales: Niello, Marco, Sideromenos, Spyridon, Gradisch, Ralph, O´Shea, Ronan, Schwazer, Jakob, Maier, Julian, Kastner, Nina, Sandtner, Walter, Jäntsch, Kathrin, Lupica, Carl R., Hoffman, Alexander F., Lubec, Gert, Loland, Claus J., Stockner, Thomas, Pollak, Daniela D., Baumann, Michael H., Sitte, Harald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963675/
https://www.ncbi.nlm.nih.gov/pubmed/36730201
http://dx.doi.org/10.1073/pnas.2114204120