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Persistent binding at dopamine transporters determines sustained psychostimulant effects
Psychostimulants interacting with the dopamine transporter (DAT) can be used illicitly or for the treatment of specific neuropsychiatric disorders. However, they can also produce severe and persistent adverse events. Often, their pharmacological properties in vitro do not fully correlate to their ph...
Autores principales: | Niello, Marco, Sideromenos, Spyridon, Gradisch, Ralph, O´Shea, Ronan, Schwazer, Jakob, Maier, Julian, Kastner, Nina, Sandtner, Walter, Jäntsch, Kathrin, Lupica, Carl R., Hoffman, Alexander F., Lubec, Gert, Loland, Claus J., Stockner, Thomas, Pollak, Daniela D., Baumann, Michael H., Sitte, Harald H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963675/ https://www.ncbi.nlm.nih.gov/pubmed/36730201 http://dx.doi.org/10.1073/pnas.2114204120 |
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