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VT-1161—A Tetrazole for Management of Mono- and Dual-Species Biofilms

VT-1161 is a novel tetrazole antifungal agent with high specificity for fungal CYP51 (compared to human CYP enzymes) which has been proven to have fewer adverse effects and drug–drug interaction profiles due to fewer off-target inhibitors. In this study, we evaluated the anti-biofilm potential of VT...

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Detalles Bibliográficos
Autores principales: Maione, Angela, Mileo, Aldo, Pugliese, Stefano, Siciliano, Antonietta, Cirillo, Luigi, Carraturo, Federica, de Alteriis, Elisabetta, De Falco, Maria, Guida, Marco, Galdiero, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963680/
https://www.ncbi.nlm.nih.gov/pubmed/36838202
http://dx.doi.org/10.3390/microorganisms11020237