Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy

Gastrin releasing peptide receptor (GRPR), a member of the bombesin (BBN) G protein-coupled receptors, is aberrantly overexpressed in several malignant tumors, including those of the breast, prostate, pancreas, lung, and central nervous system. Additionally, it also mediates non-histaminergic itch a...

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Detalles Bibliográficos
Autores principales: Peng, Shuman, Zhan, Yuting, Zhang, Dongqi, Ren, Lu, Chen, Anqi, Chen, Zhou-Feng, Zhang, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963752/
https://www.ncbi.nlm.nih.gov/pubmed/36724251
http://dx.doi.org/10.1073/pnas.2216230120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963752/
https://www.ncbi.nlm.nih.gov/pubmed/36724251
http://dx.doi.org/10.1073/pnas.2216230120

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