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Structural basis of V-ATPase V(O) region assembly by Vma12p, 21p, and 22p

Vacuolar-type adenosine triphosphatases (V-ATPases) are rotary proton pumps that acidify specific intracellular compartments in almost all eukaryotic cells. These multi-subunit enzymes consist of a soluble catalytic V(1) region and a membrane-embedded proton-translocating V(O) region. V(O) is assemb...

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Detalles Bibliográficos
Autores principales: Wang, Hanlin, Bueler, Stephanie A., Rubinstein, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963935/
https://www.ncbi.nlm.nih.gov/pubmed/36724250
http://dx.doi.org/10.1073/pnas.2217181120