Integrated regulation of dopaminergic and epigenetic effectors of neuroprotection in Parkinson’s disease models

Whole-exome sequencing of Parkinson’s disease (PD) patient DNA identified single-nucleotide polymorphisms (SNPs) in the tyrosine nonreceptor kinase-2 (TNK2) gene. Although this kinase had a previously demonstrated activity in preventing the endocytosis of the dopamine reuptake transporter (DAT), a c...

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Detalles Bibliográficos
Autores principales: Nourse, J. Brucker, Russell, Shannon N., Moniz, Nathan A., Peter, Kylie, Seyfarth, Lena M., Scott, Madison, Park, Han-A, Caldwell, Kim A., Caldwell, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963946/
https://www.ncbi.nlm.nih.gov/pubmed/36745808
http://dx.doi.org/10.1073/pnas.2210712120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963946/
https://www.ncbi.nlm.nih.gov/pubmed/36745808
http://dx.doi.org/10.1073/pnas.2210712120

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