All-Atom Molecular Dynamics Simulations Indicated the Involvement of a Conserved Polar Signaling Channel in the Activation Mechanism of the Type I Cannabinoid Receptor

The type I cannabinoid G protein-coupled receptor (CB1, GPCR) is an intensely investigated pharmacological target, owing to its involvement in numerous physiological functions as well as pathological processes such as cancers, neurodegenerative diseases, metabolic disorders and neuropathic pain. In...

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Detalles Bibliográficos
Autores principales: Sarkar, Arijit, Mitra, Argha, Borics, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963961/
https://www.ncbi.nlm.nih.gov/pubmed/36835641
http://dx.doi.org/10.3390/ijms24044232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963961/
https://www.ncbi.nlm.nih.gov/pubmed/36835641
http://dx.doi.org/10.3390/ijms24044232

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