Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease

The spleen clears altered red blood cells (RBCs) from circulation, contributing to the balance between RBC formation (erythropoiesis) and removal. The splenic RBC retention and elimination occur predominantly in open circulation where RBCs flow through macrophages and inter-endothelial slits (IESs)....

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Detalles Bibliográficos
Autores principales: Qiang, Yuhao, Sissoko, Abdoulaye, Liu, Zixiang L., Dong, Ting, Zheng, Fuyin, Kong, Fang, Higgins, John M., Karniadakis, George E., Buffet, Pierre A., Suresh, Subra, Dao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963977/
https://www.ncbi.nlm.nih.gov/pubmed/36730189
http://dx.doi.org/10.1073/pnas.2217607120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963977/
https://www.ncbi.nlm.nih.gov/pubmed/36730189
http://dx.doi.org/10.1073/pnas.2217607120

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