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Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity

χ-Conotoxins are known for their ability to selectively inhibit norepinephrine transporters, an ability that makes them potential leads for treating various neurological disorders, including neuropathic pain. PnID, a peptide isolated from the venom of Conus pennaceus, shares high sequence homology w...

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Detalles Bibliográficos
Autores principales: Espiritu, Michael J., Taylor, Jonathan K., Sugai, Christopher K., Thapa, Parashar, Loening, Nikolaus M., Gusman, Emma, Baoanan, Zenaida G., Baumann, Michael H., Bingham, Jon-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964023/
https://www.ncbi.nlm.nih.gov/pubmed/36827103
http://dx.doi.org/10.3390/md21020061