Cargando…
Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity
χ-Conotoxins are known for their ability to selectively inhibit norepinephrine transporters, an ability that makes them potential leads for treating various neurological disorders, including neuropathic pain. PnID, a peptide isolated from the venom of Conus pennaceus, shares high sequence homology w...
Autores principales: | Espiritu, Michael J., Taylor, Jonathan K., Sugai, Christopher K., Thapa, Parashar, Loening, Nikolaus M., Gusman, Emma, Baoanan, Zenaida G., Baumann, Michael H., Bingham, Jon-Paul |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964023/ https://www.ncbi.nlm.nih.gov/pubmed/36827103 http://dx.doi.org/10.3390/md21020061 |
Ejemplares similares
-
Effect of Conformational Diversity on the Bioactivity of µ-Conotoxin PIIIA Disulfide Isomers
por: Paul George, Ajay Abisheck, et al.
Publicado: (2019) -
Degradation kinetics of α‐conotoxin TxID
por: Xu, Pan, et al.
Publicado: (2019) -
Insights into the Folding of Disulfide-Rich μ-Conotoxins
por: Paul George, Ajay Abisheck, et al.
Publicado: (2018) -
‘Messy’ Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency
por: Ziegman, Rebekah, et al.
Publicado: (2019) -
DSPE-PEG Modification of α-Conotoxin TxID
por: Zhao, Weinan, et al.
Publicado: (2019)