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Celecoxib Nanoformulations with Enhanced Solubility, Dissolution Rate, and Oral Bioavailability: Experimental Approaches over In Vitro/In Vivo Evaluation

Celecoxib (CXB) is a Biopharmaceutical Classification System (BCS) Class II molecule with high permeability that is practically insoluble in water. Because of the poor water solubility, there is a wide range of absorption and limited bioavailability following oral administration. These unfavorable p...

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Detalles Bibliográficos
Autores principales: Arslan, Aslıhan, Yet, Barbaros, Nemutlu, Emirhan, Akdağ Çaylı, Yağmur, Eroğlu, Hakan, Öner, Levent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964073/
https://www.ncbi.nlm.nih.gov/pubmed/36839685
http://dx.doi.org/10.3390/pharmaceutics15020363