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Celecoxib Nanoformulations with Enhanced Solubility, Dissolution Rate, and Oral Bioavailability: Experimental Approaches over In Vitro/In Vivo Evaluation
Celecoxib (CXB) is a Biopharmaceutical Classification System (BCS) Class II molecule with high permeability that is practically insoluble in water. Because of the poor water solubility, there is a wide range of absorption and limited bioavailability following oral administration. These unfavorable p...
Autores principales: | Arslan, Aslıhan, Yet, Barbaros, Nemutlu, Emirhan, Akdağ Çaylı, Yağmur, Eroğlu, Hakan, Öner, Levent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964073/ https://www.ncbi.nlm.nih.gov/pubmed/36839685 http://dx.doi.org/10.3390/pharmaceutics15020363 |
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