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Expanding Glycomic Investigations through Thiol-Derivatized Glycans

N-(2-thioethyl)-2-aminobenzamide (TEAB), a novel glycan auxiliary, was synthesized and its utility was evaluated. The auxiliary was conjugated to glycans by reductive amination with the water-stable reagent 2-picoline borane complex. Glycan products, which ranged from 1 to 7 linked hexoses, were all...

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Detalles Bibliográficos
Autores principales: Hurst, Robert D., Nieves, Angel, Brichacek, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964202/
https://www.ncbi.nlm.nih.gov/pubmed/36838944
http://dx.doi.org/10.3390/molecules28041956