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Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration

Intervertebral disc (IVD) degeneration with Modic-like changes is strongly associated with pain. Lack of effective disease-modifying treatments for IVDs with endplate (EP) defects means there is a need for an animal model to improve understanding of how EP-driven IVD degeneration can lead to spinal...

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Detalles Bibliográficos
Autores principales: Lai, Alon, Iliff, Denise, Zaheer, Kashaf, Wang, Dalin, Gansau, Jennifer, Laudier, Damien M., Zachariou, Venetia, Iatridis, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964286/
https://www.ncbi.nlm.nih.gov/pubmed/36834838
http://dx.doi.org/10.3390/ijms24043425