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Novel Erlotinib–Chalcone Hybrids Diminish Resistance in Head and Neck Cancer by Inducing Multiple Cell Death Mechanisms

In a search for novel therapeutic options for head and neck squamous cell carcinomas (HNSCCs) generally treated with limited therapeutic success, we synthesized a series of novel erlotinib–chalcone molecular hybrids with 1,2,3-triazole and alkyne linkers and evaluated them for their anticancer activ...

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Detalles Bibliográficos
Autores principales: Murányi, József, Duró, Cintia, Gurbi, Bianka, Móra, István, Varga, Attila, Németh, Krisztina, Simon, József, Csala, Miklós, Csámpai, Antal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964293/
https://www.ncbi.nlm.nih.gov/pubmed/36834866
http://dx.doi.org/10.3390/ijms24043456