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The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model

The pathogenesis of Parkinson’s disease (PD) is very complex and still needs further exploration. Leucine-rich repeat kinase 2 (LRRK2) is associated with familial PD in mutant forms and sporadic PD in the wild-type form. Abnormal iron accumulation is found in the substantia nigra of PD patients, but...

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Detalles Bibliográficos
Autores principales: Jia, Ruru, Liu, Yanling, Shuai, Ke, Zhou, Cheng, Chen, Lei, Zhu, Li, Wu, Xiao-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964371/
https://www.ncbi.nlm.nih.gov/pubmed/36835121
http://dx.doi.org/10.3390/ijms24043709