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The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model
The pathogenesis of Parkinson’s disease (PD) is very complex and still needs further exploration. Leucine-rich repeat kinase 2 (LRRK2) is associated with familial PD in mutant forms and sporadic PD in the wild-type form. Abnormal iron accumulation is found in the substantia nigra of PD patients, but...
Autores principales: | Jia, Ruru, Liu, Yanling, Shuai, Ke, Zhou, Cheng, Chen, Lei, Zhu, Li, Wu, Xiao-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964371/ https://www.ncbi.nlm.nih.gov/pubmed/36835121 http://dx.doi.org/10.3390/ijms24043709 |
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