Synthetic Small Molecule Modulators of Hsp70 and Hsp40 Chaperones as Promising Anticancer Agents

A class of chaperones dubbed heat shock protein 70 (Hsp70) possesses high relevance in cancer diseases due to its cooperative activity with the well-established anticancer target Hsp90. However, Hsp70 is closely connected with a smaller heat shock protein, Hsp40, forming a formidable Hsp70-Hsp40 axi...

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Detalles Bibliográficos
Autores principales: Nitzsche, Bianca, Höpfner, Michael, Biersack, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964478/
https://www.ncbi.nlm.nih.gov/pubmed/36835501
http://dx.doi.org/10.3390/ijms24044083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964478/
https://www.ncbi.nlm.nih.gov/pubmed/36835501
http://dx.doi.org/10.3390/ijms24044083

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