Effects of Apigenin on Pharmacokinetics of Dasatinib and Probable Interaction Mechanism

Dasatinib (DAS), a narrow-therapeutic index drug, Bcr-Abl, and Src family kinases multitarget inhibitor have been approved for chronic myelogenous leukemia (CML) and Ph-positive acute lymphocytic leukemia (Ph+ ALL). Apigenin (APG) has a long history of human usage in food, herbs, health supplements,...

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Detalles Bibliográficos
Autores principales: Raish, Mohammad, Ahmad, Ajaz, Shahid, Mudassar, Jardan, Yousef A. Bin, Ahad, Abdul, Kalam, Mohd Abul, Ansari, Mushtaq Ahmad, Iqbal, Muzaffar, Ali, Naushad, Alkharfy, Khalid M., Al-Jenoobi, Fahad I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964503/
https://www.ncbi.nlm.nih.gov/pubmed/36838589
http://dx.doi.org/10.3390/molecules28041602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964503/
https://www.ncbi.nlm.nih.gov/pubmed/36838589
http://dx.doi.org/10.3390/molecules28041602

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