Cargando…

Effects of Apigenin on Pharmacokinetics of Dasatinib and Probable Interaction Mechanism

Dasatinib (DAS), a narrow-therapeutic index drug, Bcr-Abl, and Src family kinases multitarget inhibitor have been approved for chronic myelogenous leukemia (CML) and Ph-positive acute lymphocytic leukemia (Ph+ ALL). Apigenin (APG) has a long history of human usage in food, herbs, health supplements,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raish, Mohammad, Ahmad, Ajaz, Shahid, Mudassar, Jardan, Yousef A. Bin, Ahad, Abdul, Kalam, Mohd Abul, Ansari, Mushtaq Ahmad, Iqbal, Muzaffar, Ali, Naushad, Alkharfy, Khalid M., Al-Jenoobi, Fahad I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964503/ https://www.ncbi.nlm.nih.gov/pubmed/36838589 http://dx.doi.org/10.3390/molecules28041602

Ejemplares similares

Herb-drug interaction: Effect of sinapic acid on the pharmacokinetics of dasatinib in rats
por: Shahid, Mudassar, et al.
Publicado: (2023)

Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role
por: Raish, Mohammad, et al.
Publicado: (2021)

Sinapic Acid Ameliorates Acetic Acid-Induced Ulcerative Colitis in Rats by Suppressing Inflammation, Oxidative Stress, and Apoptosis
por: Shahid, Mudassar, et al.
Publicado: (2022)

Eudragit-Coated Sporopollenin Exine Microcapsules (SEMC) of Phoenix dactylifera L. of 5-Fluorouracil for Colon-Specific Drug Delivery
por: Raish, Mohammad, et al.
Publicado: (2021)

Sinapic Acid Ameliorates Oxidative Stress, Inflammation, and Apoptosis in Acute Doxorubicin-Induced Cardiotoxicity via the NF-κB-Mediated Pathway
por: Bin Jardan, Yousef A., et al.
Publicado: (2020)

Quality assessment of different brands of atorvastatin tablets available in Riyadh, Saudi Arabia
por: AlMuhsin, Ali, et al.
Publicado: (2022)

Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible food drug interaction
por: Raish, Mohammad, et al.
Publicado: (2018)

Assessment of glibenclamide pharmacokinetics in poloxamer 407-induced hyperlipidemic rats
por: Bin Jardan, Yousef A., et al.
Publicado: (2021)

Thermodynamic Solubility Profile of Temozolomide in Different Commonly Used Pharmaceutical Solvents
por: Ahad, Abdul, et al.
Publicado: (2022)

Formulation and characterization of eprosartan mesylate and β-cyclodextrin inclusion complex prepared by microwave technology
por: Ahad, Abdul, et al.
Publicado: (2022)

Preparation and Characterization of Transethosome Formulation for the Enhanced Delivery of Sinapic Acid
por: Bin Jardan, Yousef A., et al.
Publicado: (2023)

Identification of Doxorubicin as Repurposing Inhibitory Drug for MERS-CoV PLpro
por: Alaofi, Ahmed L., et al.
Publicado: (2022)

Hepatoprotective activity of Lepidium sativum seeds against D-galactosamine/lipopolysaccharide induced hepatotoxicity in animal model
por: Raish, Mohammad, et al.
Publicado: (2016)

Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways
por: Ansari, Mushtaq Ahmad, et al.
Publicado: (2021)

Sinapic acid alleviates 5-fluorouracil-induced nephrotoxicity in rats via Nrf2/HO-1 signalling
por: Ahmad Ansari, Mushtaq, et al.
Publicado: (2023)

Cinnamon modulates the pharmacodynamic & pharmacokinetic of amlodipine in hypertensive rats
por: Abdelrahman, Ibrahim Abdelsalam, et al.
Publicado: (2023)

Delivery of Insulin via Skin Route for the Management of Diabetes Mellitus: Approaches for Breaching the Obstacles
por: Ahad, Abdul, et al.
Publicado: (2021)

Potential pharmacodynamic and pharmacokinetic interactions of Nigella Sativa and Trigonella Foenum-graecum with losartan in L-NAME induced hypertensive rats
por: Ahad, Abdul, et al.
Publicado: (2020)

Changes in Pharmacokinetics and Pharmacodynamics of Losartan in Experimental Diseased Rats Treated with Curcuma longa and Lepidium sativum
por: Ahad, Abdul, et al.
Publicado: (2022)

Effects of garden cress, fenugreek and black seed on the pharmacodynamics of metoprolol: an herb-drug interaction study in rats with hypertension
por: Bin Jardan, Yousef A., et al.
Publicado: (2021)

The potential role of thymoquinone in preventing the cardiovascular complications of COVID-19
por: Ahmad, Ajaz, et al.
Publicado: (2021)

Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation and in silico modeling in male and female rats
por: Ahmad, Ajaz, et al.
Publicado: (2020)

Topical Sustained-Release Dexamethasone-Loaded Chitosan Nanoparticles: Assessment of Drug Delivery Efficiency in a Rabbit Model of Endotoxin-Induced Uveitis
por: Alkholief, Musaed, et al.
Publicado: (2023)

Thymoquinone modulates the expression of sepsis-related microRNAs in a CLP model
por: Alkharfy, Khalid M., et al.
Publicado: (2022)

Effects of Nigella sativa and Lepidium sativum on Cyclosporine Pharmacokinetics
por: Al-Jenoobi, F. I., et al.
Publicado: (2013)

Perspectives of Positively Charged Nanocrystals of Tedizolid Phosphate as a Topical Ocular Application in Rabbits
por: Alshememry, Abdullah, et al.
Publicado: (2022)

Systemic delivery of β-blockers via transdermal route for hypertension
por: Ahad, Abdul, et al.
Publicado: (2015)

Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model
por: Ahmad, Ajaz, et al.
Publicado: (2019)

Mesoporous Silica Nanoparticles Coated with Carboxymethyl Chitosan for 5-Fluorouracil Ocular Delivery: Characterization, In Vitro and In Vivo Studies
por: Alhowyan, Adel Ali, et al.
Publicado: (2023)

Antithrombocytopenic and immunomodulatory potential of metabolically characterized aqueous extract of Carica papaya leaves
por: Anjum, Varisha, et al.
Publicado: (2017)

Formulation and Evaluation of Apigenin-Loaded Hybrid Nanoparticles
por: Kazmi, Imran, et al.
Publicado: (2022)

Spasmolytic and Uroprotective Effects of Apigenin by Downregulation of TGF-β and iNOS Pathways and Upregulation of Antioxidant Mechanisms: In Vitro and In Silico Analysis
por: , Saima, et al.
Publicado: (2023)

Apigenin Loaded Lipoid–PLGA–TPGS Nanoparticles for Colon Cancer Therapy: Characterization, Sustained Release, Cytotoxicity, and Apoptosis Pathways
por: Alfaleh, Mohamed A., et al.
Publicado: (2022)

Development and Evaluation of Chitosan Nanoparticles for Ocular Delivery of Tedizolid Phosphate
por: Kalam, Mohd Abul, et al.
Publicado: (2022)

Fabrication and Characterization of Tedizolid Phosphate Nanocrystals for Topical Ocular Application: Improved Solubilization and In Vitro Drug Release
por: Kalam, Mohd Abul, et al.
Publicado: (2022)

Formulation and characterization of novel soft nanovesicles for enhanced transdermal delivery of eprosartan mesylate
por: Ahad, Abdul, et al.
Publicado: (2017)

The Potential Protective Role of Naringenin against Dasatinib-Induced Hepatotoxicity
por: Alanazi, Ahmed Z., et al.
Publicado: (2023)

Dasatinib-Induced Colitis with Rectal Sparing in a Patient with Chronic Myeloid Leukemia (Chronic Phase) on Dasatinib as an Upfront Therapy: Case Report
por: Maat, Zakaria, et al.
Publicado: (2021)

Development and validation of bioanalytical UHPLC-UV method for simultaneous analysis of unchanged fenofibrate and its metabolite fenofibric acid in rat plasma: Application to pharmacokinetics
por: Alamri, Rayan G., et al.
Publicado: (2017)

Effect of Itraconazole on the Pharmacokinetics of Diclofenac in Beagle Dogs
por: Al-Jenoobi, Fahad I.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_uqu3k99c8m6rdtt4k4sbvlf2ln