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Structure Determination of Felodipine Photoproducts in UV-Irradiated Medicines Using ESI-LC/MS/MS

Dihydropyridine drugs are well known as photodegradable pharmaceuticals. Herein, we evaluate the photostability of felodipine (FL) medicine (Splendil(®) (SPL) tablets) and its altered forms (powders and suspensions). FL is a type of dihydropyridine drug, but its photochemical behavior is unknown. FL...

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Detalles Bibliográficos
Autores principales: Kawabata, Kohei, Kohashi, Miya, Akimoto, Shiori, Nishi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964566/
https://www.ncbi.nlm.nih.gov/pubmed/36840019
http://dx.doi.org/10.3390/pharmaceutics15020697