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Bio-Oriented Synthesis and Molecular Docking Studies of 1,2,4-Triazole Based Derivatives as Potential Anti-Cancer Agents against HepG2 Cell Line

Triazole-based acetamides serve as important scaffolds for various pharmacologically active drugs. In the present work, structural hybrids of 1,2,4-triazole and acetamides were furnished by chemically modifying 2-(4-isobutylphenyl) propanoic acid (1). Target compounds 7a–f were produced in considera...

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Detalles Bibliográficos
Autores principales: Akhter, Naheed, Batool, Sidra, Khan, Samreen Gul, Rasool, Nasir, Anjum, Fozia, Rasul, Azhar, Adem, Şevki, Mahmood, Sadaf, Rehman, Aziz ur, Nisa, Mehr un, Razzaq, Zainib, Christensen, Jørn B., Abourehab, Mohammed A. S., Shah, Syed Adnan Ali, Imran, Syahrul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964635/
https://www.ncbi.nlm.nih.gov/pubmed/37259360
http://dx.doi.org/10.3390/ph16020211