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Discovery of Ureido-Based Apcin Analogues as Cdc20-specific Inhibitors against Cancer
Cdc20 is a promising drug target that plays an important role in the mid-anaphase process of cellular mitosis, and Apcin is the only reported core structure of the Cdc20-specific inhibitor. Some potent Apcin derivatives were obtained in our previous research, and a structure–activity relationship wa...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964651/ https://www.ncbi.nlm.nih.gov/pubmed/37259447 http://dx.doi.org/10.3390/ph16020304 |