Developing In Situ Chemometric Models with Raman Spectroscopy for Monitoring an API Disproportionation with a Complex Polymorphic Landscape

An in situ Raman method was developed to characterize the disproportionation of two salts involving a complex polymorphic landscape comprising up to two metastable and one stable freebase forms. Few precedents exist for Raman calibration procedures for solid form quantitation involving more than two...

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Detalles Bibliográficos
Autores principales: Mohan, Shikhar, Li, Yi, Chu, Kevin, Shi, Bing, De La Paz, Liliana, Bakre, Prarthana, Foti, Chris, Rucker, Victor, Lai, Chiajen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964727/
https://www.ncbi.nlm.nih.gov/pubmed/37259469
http://dx.doi.org/10.3390/ph16020327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964727/
https://www.ncbi.nlm.nih.gov/pubmed/37259469
http://dx.doi.org/10.3390/ph16020327

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