CBL/CAP Is Essential for Mitochondria Respiration Complex I Assembly and Bioenergetics Efficiency in Muscle Cells

CBL is rapidly phosphorylated upon insulin receptor activation. Mice whole body CBL depletion improved insulin sensitivity and glucose clearance; however, the precise mechanisms remain unknown. We depleted either CBL or its associated protein SORBS1/CAP independently in myocytes and assessed mitocho...

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Detalles Bibliográficos
Autores principales: Aye, Cho-Cho, Hammond, Dean E., Rodriguez-Cuenca, Sergio, Doherty, Mary K., Whitfield, Phillip D., Phelan, Marie M., Yang, Chenjing, Perez-Perez, Rafael, Li, Xiaoxin, Diaz-Ramos, Angels, Peddinti, Gopal, Oresic, Matej, Vidal-Puig, Antonio, Zorzano, Antonio, Ugalde, Cristina, Mora, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964740/
https://www.ncbi.nlm.nih.gov/pubmed/36834818
http://dx.doi.org/10.3390/ijms24043399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964740/
https://www.ncbi.nlm.nih.gov/pubmed/36834818
http://dx.doi.org/10.3390/ijms24043399

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