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Nanoseeded Desupersaturation and Dissolution Tests for Elucidating Supersaturation Maintenance in Amorphous Solid Dispersions

The impact of residual drug crystals that are formed during the production and storage of amorphous solid dispersions (ASDs) has been studied using micron-sized seed crystals in solvent-shift (desupersaturation) and dissolution tests. This study examines the impacts of the seed size loading on the s...

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Detalles Bibliográficos
Autores principales: Guner, Gulenay, Amjad, Ayesha, Berrios, Matthew, Kannan, Manisha, Bilgili, Ecevit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964794/
https://www.ncbi.nlm.nih.gov/pubmed/36839772
http://dx.doi.org/10.3390/pharmaceutics15020450